(8S)-2-(2,5-dimethoxyphenyl)-6-(thiophen-2-ylmethyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione

• ChemBase ID: 202143
• Molecular Formular: C27H25N3O4S
• Molecular Mass: 487.5701
• Monoisotopic Mass: 487.1565773
• SMILES: N12C(c3c(C[C@H]1C(=O)N(CC2=O)Cc1sccc1)c1c([nH]3)cccc1)c1c(ccc(c1)OC)OC
• Canonical SMILES: COc1ccc(cc1C1N2C(=O)CN(C(=O)[C@@H]2Cc2c1[nH]c1c2cccc1)Cc1cccs1)OC
• InChI: InChI=1S/C27H25N3O4S/c1-33-16-9-10-23(34-2)20(12-16)26-25-19(18-7-3-4-8-21(18)28-25)13-22-27(32)29(15-24(31)30(22)26)14-17-6-5-11-35-17/h3-12,22,26,28H,13-15H2,1-2H3/t22-,26?/m0/s1
• InChIKey: WQPXCHMOIGUJHS-CHQVSRGASA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: (8S)-2-(2,5-dimethoxyphenyl)-6-(thiophen-2-ylmethyl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione
• IUPAC Traditional name: (8S)-2-(2,5-dimethoxyphenyl)-6-(thiophen-2-ylmethyl)-3,6,17-triazatetracyclo[8.7.0.0^3,^8.0^1^1,^1^6]heptadeca-1(10),11,13,15-tetraene-4,7-dione

Database IDs

• PubChem SID: 164258053
• PubChem CID: 16400002

CALCULATED PROPERTIES

• Acid pKa: 15.167735
• H Acceptors: 4
• H Donor: 1
• LogD (pH = 5.5): 3.3381188
• LogD (pH = 7.4): 3.3381188
• Log P: 3.3381188
• Molar Refractivity: 132.7436 cm^3
• Polarizability: 52.24197 Å^3
• Polar Surface Area: 74.87 Å^2
• Rotatable Bonds: 5
• Lipinski's Rule of Five: true

PROPERTIES

Product Information

• Classification: Derivatives & analogs of Natural Compounds