potassiobis(trimethylsilyl)amine

• ChemBase ID: 129053
• Molecular Formular: C6H18KNSi2
• Molecular Mass: 199.48312
• Monoisotopic Mass: 199.06148433
• SMILES: C[Si](C)(C)N([K])[Si](C)(C)C
• Canonical SMILES: [K]N([Si](C)(C)C)[Si](C)(C)C
• InChI: InChI=1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• InChIKey: IUBQJLUDMLPAGT-UHFFFAOYSA-N

NAMES AND DATABASE IDS

Names

• IUPAC name: potassiobis(trimethylsilyl)amine
• IUPAC Traditional name: potassiobis(trimethylsilyl)amine
• Synonyms: Potassium hexamethyldisilazide; Potassium bis(trimethylsilyl)amide; Hexamethyldisilazane potassium salt; Potassium bis(trimethylsilyl)amide; Hexamethyldisilazane potassium salt solution; Potassium hexamethyldisilazide solution; Potassium bis(trimethylsilyl)amide solution; 六甲基二硅基胺基钾; 六甲基二硅氮烷 钾盐; 双(三甲基硅烷基)氨基钾; 六甲基二硅基胺基钾 溶液; 六甲基二硅氮烷 钾盐 溶液; 双(三甲基硅烷基)氨基钾 溶液

Database IDs

• CAS Number: 40949-94-8
• MDL Number: MFCD00010330
• Beilstein Number: 4006754
• PubChem SID: 24856751; 24859460; 162223353
• PubChem CID: 3251421
• Chemspider ID: 21171158
• Wikipedia Title: Potassium_bis(trimethylsilyl)amide

CALCULATED PROPERTIES

• H Acceptors: 1
• H Donor: 0
• LogD (pH = 5.5): -2.0271168
• LogD (pH = 7.4): -1.5891488
• Log P: -1.5074
• Molar Refractivity: 38.699 cm^3
• Polarizability: 21.345957 Å^3
• Polar Surface Area: 3.24 Å^2
• Rotatable Bonds: 2
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: Reacts in water
• Apperance: clear to slightly hazy yellow; White, opaque crystals
• Flash Point: -.4 °F; -18 °C; 44.6 °F; 7 °C
• Density: 0.877 g/mL at 25 °C; 0.915 g/mL at 25 °C
• Vapor Pressure: 54 mmHg ( 25 °C)
• Vapor Density: 3.2 (vs air)

Safety Information

• European Hazard Symbols: Corrosive (C); Flammable (F); Irritant (Xi)
• UN Number: 2924; 3263
• German water hazard class: 3
• Hazard Class: 3; 8
• Packing Group: 2; 3
• Risk Statements: 11-14-19-36/37/38; 14-34; 63-11-14-34-48/20-65-67; R14, R34
• Safety Statements: 16-26; 16-26-36/37/39-45-62; 26-36/37/39-43-45; S26, S36/37/39, S43, S45
• GHS Pictograms: GHS corrosion; GHS02; GHS05; GHS07; GHS08
• GHS Signal Word: DANGER; Danger
• GHS Hazard statements: 314; H225-H304-H314-H336-H361d-H373; H225-H314-H335; H314
• GHS Precautionary statements: 280, 305+351+338, 310; P210-P261-P280-P301 + P310-P305 + P351 + P338-P310; P210-P261-P280-P305 + P351 + P338-P310; P280-P305 + P351 + P338-P310
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges; Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• RID/ADR: UN 2924 3/PG 2; UN 3263 8/PG 3
• Supplemental Hazard Statements: May form explosive peroxides., Reacts violently with water.; Reacts violently with water.

Product Information

• Purity: ≥95.0% (T); 95%
• Concentration: 0.5 M in toluene; 1 M in THF
• Grade: purum
• Linear Formula: [(CH3)3Si]2NK

DETAILS

Sigma Aldrich - 277304

Application
Strong base used in the alkylation carbonyl compounds.1
Packaging
4×25, 100, 800 mL in Sure/Seal™

Sigma Aldrich - 702722

Packaging
4×25, 100, 500 mL in Sure/Seal™

Sigma Aldrich - 324671

Packaging
5, 25, 100 g in glass bottle
Application
Anionic initiator used in the preparation of poly(ethylene oxide).1 Sterically hindered base employed in selective cyclization reactions.2 Also used in the preparation of lanthanide complexes.3,4