Home > Compound List > Compound details
50-01-1 molecular structure
click picture or here to close

guanidine hydrochloride

ChemBase ID: 102498
Molecular Formular: CH6ClN3
Molecular Mass: 95.53144
Monoisotopic Mass: 95.02502489
SMILES and InChIs

SMILES:
Cl.NC(=N)N
Canonical SMILES:
NC(=N)N.Cl
InChI:
InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
InChIKey:
PJJJBBJSCAKJQF-UHFFFAOYSA-N

Cite this record

CBID:102498 http://www.chembase.cn/molecule-102498.html

Collapse All Expand All

NAMES AND DATABASE IDS

NAMES AND DATABASE IDS

Names Database IDs
IUPAC name
guanidine hydrochloride
IUPAC Traditional name
guanidine hydrochloride
Synonyms
Guanidine (Aminoformamidine) HCl
GUANIDINE HYDROCHLORIDE, ULTRA PURE
Aminoformamidine hydrochloride
Aminomethanamidine hydrochloride
Guanidinium chloride
GUANIDINE HYDROCHLORIDE PRACTICAL GRADE
Guanidium chloride
GUANIDINE HYDROCHLORIDE ULTRA PURE
GUANIDINE HYDROCHLORIDE
Guanidine hydrochloride solution
Guanidine hydrochloride
Guanidine hydrochloride
Guanidinium chloride
胍盐酸盐
胍 盐酸盐 溶液
亚氨基脲 盐酸盐
亚氨脲 盐酸盐
盐酸胍
胍 盐酸盐
盐酸胍
CAS Number
50-01-1
EC Number
200-002-3
MDL Number
MFCD00013026
Beilstein Number
3591990
Merck Index
144562
PubChem SID
24873457
24895181
24873454
24895119
24873455
24895369
162089942
24873453
24873456
24895295
24895176
PubChem CID
10855382
5742
CHEBI ID
32735
Chemspider ID
5540
Unique Ingredient Identifier
3YQC9ZY4YB
Wikipedia Title
Guanidinium_chloride

CALCULATED PROPERTIES

CALCULATED PROPERTIES

JChem
H Acceptors H Donor
LogD (pH = 5.5) -3.6522877  LogD (pH = 7.4) -3.6514976 
Log P -1.236839  Molar Refractivity 25.8588 cm3
Polarizability 5.61125 Å3 Polar Surface Area 75.89 Å2
Rotatable Bonds Lipinski's Rule of Five true 

PROPERTIES

PROPERTIES

Physical Property Safety Information Pharmacology Properties Product Information Bioassay(PubChem)
Solubility
H2O: soluble6 M expand Show data source
H2O: soluble6 M at 20 °C, clear, colorless expand Show data source
H2O: soluble6 M, clear (100 Hazen) expand Show data source
H2O: soluble6 M, clear, colorless expand Show data source
very soluble in water and ethanol expand Show data source
Apperance
orthorhombic bipyramidal crystals expand Show data source
Melting Point
178-185°C expand Show data source
180-185 °C(lit.) expand Show data source
182.3°C expand Show data source
184 °C expand Show data source
Density
1.18 g/mL at 25 °C(lit.) expand Show data source
1.344 expand Show data source
1.345 g/cm3 at 20 °C expand Show data source
1.354 g/cm3 at 20 °C expand Show data source
Refractive Index
n20/D 1.465 expand Show data source
Absorption Wavelength
A6M/260 nm, H2O ≤0.10 expand Show data source
A6M/260, H2O ≤0.1 expand Show data source
A6M/280, H2O ≤0.05 expand Show data source
λ: 260 nm Amax: 0.03 expand Show data source
λ: 260 nm Amax: 0.040 expand Show data source
λ: 280 nm Amax: 0.02 expand Show data source
λ: 280 nm Amax: 0.025 expand Show data source
Hydrophobicity(logP)
-2.387 expand Show data source
pH
4.5-6.0 (25 °C, 6 M in H2O) expand Show data source
4.5-6.0 (6 M in H2O) expand Show data source
4.5-7.5 (25 °C) expand Show data source
Storage Condition
Room Temperature (15-30°C) expand Show data source
Room Temperature (15-30°C), Desiccate expand Show data source
Storage Warning
Hygroscopic expand Show data source
RTECS
MF4300000 expand Show data source
European Hazard Symbols
X expand Show data source
Harmful Harmful (Xn) expand Show data source
MSDS Link
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
German water hazard class
1 expand Show data source
2 expand Show data source
Risk Statements
22-36/38 expand Show data source
R:22-36/38 expand Show data source
Safety Statements
22 expand Show data source
26 expand Show data source
S:22 expand Show data source
TSCA Listed
expand Show data source
GHS Pictograms
GHS07 expand Show data source
GHS Signal Word
Warning expand Show data source
GHS Hazard statements
H302-H315-H319 expand Show data source
GHS Precautionary statements
P280-P305+P351+P338-P302+P352-P321-P362-P501A expand Show data source
P305 + P351 + P338 expand Show data source
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves expand Show data source
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter expand Show data source
Target
Others expand Show data source
Purity
≥99% expand Show data source
~99% expand Show data source
>99% expand Show data source
≥98% expand Show data source
≥99% expand Show data source
≥99% (titration) expand Show data source
≥99.0% expand Show data source
≥99.0% (AT) expand Show data source
≥99.5% expand Show data source
≥99.5% (AT) expand Show data source
≥99.5% (titration) expand Show data source
92% expand Show data source
95% expand Show data source
98% expand Show data source
99% expand Show data source
Concentration
~8 M in H2O expand Show data source
8 M in H2O (filtered) expand Show data source
Grade
for analytical purposes expand Show data source
for molecular biology expand Show data source
OPTICAL expand Show data source
PRACTICAL expand Show data source
SAJ special grade expand Show data source
Salt Data
HCl expand Show data source
Certificate of Analysis
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Download expand Show data source
Ignition Residue
≤0.05% expand Show data source
≤0.05% (as SO4) expand Show data source
≤0.1% (as SO4) expand Show data source
≤0.2% (as SO4) expand Show data source
Impurities
DNases, none detected expand Show data source
Insoluble matter, passes filter test expand Show data source
insoluble matter, passes filter test expand Show data source
phosphatases, none detected expand Show data source
proteases, none detected expand Show data source
RNases, none detected expand Show data source
Cation Traces
Al: ≤0.0005% expand Show data source
Al: ≤1 mg/kg expand Show data source
Al: ≤5 mg/kg expand Show data source
As: ≤0.0001% expand Show data source
As: ≤0.1 mg/kg expand Show data source
Ba: ≤0.0005% expand Show data source
Ba: ≤1 mg/kg expand Show data source
Ba: ≤5 mg/kg expand Show data source
Bi: ≤0.0005% expand Show data source
Bi: ≤1 mg/kg expand Show data source
Bi: ≤5 mg/kg expand Show data source
Ca: ≤0.001% expand Show data source
Ca: ≤10 mg/kg expand Show data source
Ca: ≤20 mg/kg expand Show data source
Ca: ≤5 mg/kg expand Show data source
Cd: ≤0.0005% expand Show data source
Cd: ≤1 mg/kg expand Show data source
Cd: ≤5 mg/kg expand Show data source
Co: ≤0.0005% expand Show data source
Co: ≤1 mg/kg expand Show data source
Co: ≤5 mg/kg expand Show data source
Cr: ≤0.0005% expand Show data source
Cr: ≤1 mg/kg expand Show data source
Cr: ≤5 mg/kg expand Show data source
Cu: ≤0.0005% expand Show data source
Cu: ≤1 mg/kg expand Show data source
Cu: ≤5 mg/kg expand Show data source
Fe: ≤0.0005% expand Show data source
Fe: ≤1 mg/kg expand Show data source
Fe: ≤5 mg/kg expand Show data source
K: ≤0.005% expand Show data source
K: ≤20 mg/kg expand Show data source
K: ≤50 mg/kg expand Show data source
Li: ≤0.0005% expand Show data source
Li: ≤1 mg/kg expand Show data source
Li: ≤5 mg/kg expand Show data source
Mg: ≤0.0005% expand Show data source
Mg: ≤1 mg/kg expand Show data source
Mg: ≤5 mg/kg expand Show data source
Mn: ≤0.0005% expand Show data source
Mn: ≤1 mg/kg expand Show data source
Mn: ≤5 mg/kg expand Show data source
Mo: ≤0.0005% expand Show data source
Mo: ≤1 mg/kg expand Show data source
Mo: ≤5 mg/kg expand Show data source
Na: ≤0.005% expand Show data source
Na: ≤20 mg/kg expand Show data source
Na: ≤50 mg/kg expand Show data source
Ni: ≤0.0005% expand Show data source
Ni: ≤1 mg/kg expand Show data source
Ni: ≤5 mg/kg expand Show data source
Pb: ≤0.0005% expand Show data source
Pb: ≤1 mg/kg expand Show data source
Pb: ≤5 mg/kg expand Show data source
Pb: ≤5 ppm expand Show data source
Sr: ≤0.0005% expand Show data source
Sr: ≤1 mg/kg expand Show data source
Sr: ≤5 mg/kg expand Show data source
Zn: ≤0.0005% expand Show data source
Zn: ≤1 mg/kg expand Show data source
Zn: ≤5 mg/kg expand Show data source
Antion Traces
sulfate (SO42-): ≤0.005% expand Show data source
sulfate (SO42-): ≤50 mg/kg expand Show data source
Contains
≤0.4% SiO2 as anticaking agent expand Show data source
Foreign Activity
DNase, RNase, none detected expand Show data source
Loss on Drying
≤0.05% loss on drying, 20 °C (HV) expand Show data source
≤0.05% loss on drying, HV, 20°C expand Show data source
≤0.5% loss on drying, 20 °C (HV) expand Show data source
Quality Level
ELITE expand Show data source
λ
6 M in H2O expand Show data source
neat expand Show data source
Product Line
BioUltra expand Show data source
Linear Formula
NH2C(=NH)NH2 · HCl expand Show data source
Empirical Formula (Hill Notation)
CH5N3 · HCl expand Show data source

DETAILS

DETAILS

MP Biomedicals MP Biomedicals Wikipedia Wikipedia Sigma Aldrich Sigma Aldrich
MP Biomedicals - 02194826 external link
Molecular Biology Reagent
Purity: 99+%
MP Biomedicals - 02105696 external link
Crystalline
Purity: >9%
Forms clear, colorless solutions at 6.0 M concentration.
O.D. 260 nm of a 6.0 M solution: 0<03.
MP Biomedicals - 04820512 external link
Purity: >99% O.D. (260 nm) of a 6 M solution: <0.03 Ammeline: none detected Protein denaturant for molecular weight determinations.
MP Biomedicals - 02151210 external link
Optical Grade
Crystalline
Purity: ~99%
Produces clear, colorless solutions
MP Biomedicals - 04820539 external link
Purity: >99%
O.D. (260 nm) of a 6 M solution: <0.03
Ammeline: none detected
Protein denaturant for molecular weight determinations.
MP Biomedicals - 04820540 external link
Purity: >99% O.D. (260 nm) of a 6 M solution: <0.03 Ammeline: none detected Protein denaturant for molecular weight determinations.
MP Biomedicals - 02101905 external link
Practical Grade, solution may be cloudy and yellow.
Crystalline
2-3% Water Insolubles
Sigma Aldrich - 50950 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Packaging
1, 2.5 kg in poly bottle
250 g in poly bottle
Sigma Aldrich - G7153 external link
Application
强效离液剂,用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质,如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。
Sigma Aldrich - 50935 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Other Notes
In the extraction and fractionation by cesium sulfate density gradient centrifugation of bovine nasal cartilage proteoglycan1; Induces subunit dissociation and unfolding of bovine liver glutamate dehydrogenase2; Dissociation of apolipoproteins of insect lipophorin3; Denaturation curve4.
Sigma Aldrich - G3272 external link
Application
强效离液剂,用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质,如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。
Sigma Aldrich - G4505 external link
Application
强效离液剂,用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质,如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。
包装
1 kg in poly bottle
2, 10, 25 kg in poly drum
25, 100, 500 g in poly bottle
Sigma Aldrich - 12-1665 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Suitability
for biological purposes
Sigma Aldrich - 177253 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Packaging
100 g in poly bottle
Sigma Aldrich - 77839 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Sigma Aldrich - 12-1660 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Sigma Aldrich - G4630 external link
Application
强效离液剂,用于蛋白质的变性以及后续复性。该强效变性剂可溶解不溶性或变性的蛋白质,如包涵体。可用作使蛋白质或酶复性为活性形式的第一步骤。可能还需要脲和二硫苏糖醇 (DTT)。
Sigma Aldrich - 50933 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Other Notes
Denaturant. Isolation of RNA1
Sigma Aldrich - G11705 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
Packaging
1 kg in poly bottle
Sigma Aldrich - 50939 external link
Application
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

REFERENCES

REFERENCES

From Suppliers Google Scholar IconGoogle Scholar PubMed iconPubMed Google Books IconGoogle Books
    No data available
  • Searching...Please wait...

PATENTS

PATENTS

PubChem iconPubChem Patent Google Patent Search IconGoogle Patent

INTERNET

INTERNET

Baidu iconBaidu google iconGoogle