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Hesperetin

Catalog No. DB01094 Name DrugBank
CAS Number 520-33-2 Website http://www.ualberta.ca/
M. F. C16H14O6 Telephone (780) 492-3111
M. W. 302.27876 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 965

SYNONYMS

IUPAC name
(2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
IUPAC Traditional name
hesperetin
Brand Name
Hesperin
Synonyms
YSO2
Hesperitin
Cyanidanon 4'-Methyl Ether 1626

DATABASE IDS

PubChem SID 46507998
PubChem CID 72281
CAS Number 520-33-2

PROPERTIES

Hydrophobicity(logP) 1.1
Solubility 273 mg/L

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
Indication For lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity, as well as activity again.
Pharmacology Hesperetin is a cholesterol lowering flavanoid found in a number of citrus juices. It appears to reduce cholesteryl ester mass and inhibit apoB secretion by up to 80%. Hesperetin may have antioxidant, anti-inflammatory, anti-allergic, hypolipidemic, vasoprotective and anticarcinogenic actions.
Affected Organisms
Humans and other mammals
External Links
Wikipedia
PDRhealth

REFERENCES