| Item |
Information |
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Drug Groups
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approved |
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Description
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A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. [PubChem] |
| Indication |
For general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex. |
| Pharmacology |
Benzocaine is a local anesthetic commonly used as a topical pain reliever. It is the active ingredient in many over-the-counter analgesic ointments. It is also indicated for general use as a lubricant and topical anesthetic on intratracheal catheters and pharyngeal and nasal airways to obtund the pharyngeal and tracheal reflexes; on nasogastric and endoscopic tubes; urinary catheters; laryngoscopes; proctoscopes; sigmoidoscopes and vaginal specula. |
| Toxicity |
LD50=3040 mg/kg (rat, oral) |
| Affected Organisms |
| • |
Humans and other mammals |
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| External Links |
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