Deslanoside

• Catalog No.: DB01078
• CAS Number: 17598-65-1
• M. F.: C47H74O19
• M. W.: 943.07906

SYNONYMS

• IUPAC name: 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-5-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one
• IUPAC Traditional name: deslanoside
• Brand Name: Cedilanid-d; Deacetyllanatoside C

DATABASE IDS

• CAS Number: 17598-65-1

PROPERTIES

• Hydrophobicity(logP): 0.2

DETAILS

Description (English)

• Drug Groups: approved
• Description: Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata. [PubChem]
• Indication: For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
• Pharmacology: Deslanoside is a cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.
• Toxicity: Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.
• Affected Organisms: Humans and other mammals
• Absorption: Little absorption from the gastrointestinal tract (40%).
• Half Life: 36 hours
• Protein Binding: 20%
• External Links: Wikipedia