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Mimosine

Catalog No. DB01055 Name DrugBank
CAS Number 500-44-7 Website http://www.ualberta.ca/
M. F. C8H10N2O4 Telephone (780) 492-3111
M. W. 198.176 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 926

SYNONYMS

IUPAC name
(2S)-2-amino-3-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid
IUPAC Traditional name
mimosine
Synonyms
Leucaenol
L-Mimosine
Leucenol
Leucaenine
Leucenine
Mimosin

DATABASE IDS

CAS Number 500-44-7
PubChem SID 46505895
PubChem CID 440473

PROPERTIES

Hydrophobicity(logP) -2.5

DETAILS

Description (English)
Item Information
Drug Groups approved
Description 3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca. [PubChem]
Pharmacology Mimosine inhibits DNA synthesis at the level of elongation of nascent chains by altering deoxyribonucleotide metabolism. It arrests the cell cycle in the late G(1) phase.
Affected Organisms
Humans and other mammals
Protein Binding >99.5%
External Links
Wikipedia

REFERENCES