Oseltamivir phosphate

• Catalog No.: S2597
• CAS Number: 204255-11-8
• M. F.: C16H29N2O8P
• M. W.: 408.383821
• Storage: -20°C

SYNONYMS

• IUPAC name: phosphoperoxol ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate hydrogen
• IUPAC Traditional name: oseltamivir phosphoperoxol hydrogen(.)
• Synonyms: Tamiflu

DATABASE IDS

• CAS Number: 204255-11-8

PROPERTIES

• Salt Data: phosphate
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its active metabolite, the free carboxylate of oseltamivir (GS4071). Oseltamivir phosphate (Tamiflu) serves as a competitive inhibitor towards sialic acid, found on the surface proteins of normal host cells. By blocking the activity of the viral neuraminidase enzyme, oseltamivir phosphate (Tamiflu) prevents new viral particles from being released by infected cells. Oseltamivir phosphate (Tamiflu) is an antiviral drug that slows the spread of influenza (flu) virus between cells in the body by stopping the virus from chemically cutting ties with its host cell. [1][2][3] References on Oseltamivir phosphate (Tamiflu)[1] http://en.wikipedia.org/wiki/Oseltamivir, , [2] PLoS Comput Biol., 2010 Sep 23, 6(9)[3] Microbes Infect., 2010 Sep, 12(10):778-83

REFERENCES

• Le L et al. PLoS Comput Biol. 2010 Sep 23; 6(9).