Benidipine hydrochloride

• Catalog No.: S2017
• CAS Number: 91599-74-5
• M. F.: C28H32ClN3O6
• M. W.: 542.02318
• Storage: -20°C

SYNONYMS

• IUPAC name: 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• IUPAC Traditional name: benidipine hydrochloride

DATABASE IDS

• CAS Number: 91599-74-5

PROPERTIES

• Target: calcium channel
• Salt Data: hydrochloride
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: cancer
Biological Activity:
Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. [1] Benidipine hydrochloride is used for the treatment of high blood pressure (hypertension). Benidipine hydrochloride reveals a wide range of activities in vitro and in vivo. Benidipine hydrochloride inhibits L-, N- and T-type Ca2+ channels. Benidipine hydrochloride also prevents aldosterone- induced mineralocorticoid receptor activation. Benidipine hydrochloride exhibits cardioprotective and antiartherosclerotic effects. [2]References on Benidipine HCl[1] http://en.wikipedia.org/wiki/Benidipine, , [2] Eur J Pharmacol., 2010, 635(1-3):49-55

REFERENCES

• Kosaka H,et al. Eur J Pharmacol. 2010;635(1-3):49-55.