Sodium metaperiodate

• Catalog No.: 13798
• CAS Number: 7790-28-5
• M. F.: INaO4
• M. W.: 213.89184
• Purity: 98%

SYNONYMS

• Title: 高碘酸钠
• IUPAC name: sodium periodate
• IUPAC Traditional name: sodium periodate
• Synonyms: Sodium periodate

DATABASE IDS

• CAS Number: 7790-28-5
• Merck Index: 148640
• EC Number: 232-197-6
• MDL Number: MFCD00003534

PROPERTIES

• Purity: 98%
• Apperance: Powder
• Density: 3.86
• Melting Point: 300°C dec.
• Solubility: Soluble in water and acids
• GHS Hazard statements: H272-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• European Hazard Symbols: Oxidising (O)
• GHS Precautionary statements: P221-P210-P305+P351+P338-P302+P352-P405-P501A
• Risk Statements: 8-36/37/38
• RTECS: SD4550000
• Safety Statements: 17-26-37
• Storage Warning: Hygroscopic
• TSCA Listed: 是
• Hazard Class: 5.1
• UN Number: UN1479
• Packing Group: II

REFERENCES

• For review of use in the cleavage of 1,2-diols to carbonyl compounds, see: Synthesis, 229 (1974). For application to the high-yield, racemization-free preparation of the useful intermediate isopropylidene-D-glyceraldehyde, see: Synth. Commun., 18, 337 (1988). See also: Org. Synth. Coll., 9, 450, 454 (1998).
• This reaction can be extended to the cleavage of alkenes, by use in conjunction with a reagent for the hydroxylation of alkenes, which can be regenerated by reoxidation by periodate. For use in combination with KMnO₄ (Lemieux-von Rudloff reagent), see: Can. J. Chem., 33, 1701, 1710 (1955), for cleavage of a steroidal enone, see: Org. Synth. Coll., 6, 690 (1988). The combination with OsO₄ is known as the Lemieux-Johnson reagent: J. Org. Chem., 21, 478 (1956); Synthesis, 45 (1989).
• For use in the in situ regeneration of RuO₄,see Ruthenium(III) chloride hydrate, 11043.
• Useful for selective oxidation of sulfides to sulfoxides; see, for example: Org. Synth. Coll., 9, 63 (1998).
• Alkyl halides, on heating with NaIO₄ in DMF, can be oxidized to aldehydes or ketones: Tetrahedron Lett., 44, 1375 (2003). For use, in the presence of Dibenzo-18-crown-6, A13133, in the oxidative decarboxylation of arylacetic acids to benzaldehydes and of phenacyl bromides to benzoic acids, see: Indian J. Chem. B, 35B, 151 (1996).