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Ceftiofur hydrochloride _Molecular_structure_CAS_103980-44-5)
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Ceftiofur hydrochloride

Catalog No. S2543 Name Selleck Chemicals
CAS Number 103980-44-5 Website http://www.selleckchem.com
M. F. C19H18ClN5O7S3 Telephone (877) 796-6397
M. W. 560.02352 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 73093


IUPAC name
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
IUPAC Traditional name
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride


CAS Number 103980-44-5


Salt Data hydrochloride
Storage Condition -20°C


Description (English)
Research Area: Infection
Biological Activity:
Ceftiofur hydrochloride is a hydrochloride of ceftiofur that is a broad spectrum cephalosporin. Ceftiofur hydrochloride is resistant to the antibiotic resistance enzyme beta-lactamase. Ceftiofur hydrochloride has activity against Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. Ceftiofur was more active than was ampicillin against all strains tested including beta-lactamase-producing organisms. In mice with systemic infections, ceftiofur was more active than or equivalent to ampicillin, cephalothin, cefamandole, cloxacillin, cefoperazone, or pirlimycin. These protection tests included infections with Escherichia coli, Haemophilus pleuropneumoniae, H somnus, Pasteurella haemolytica, P multocida, Salmonella typhimurium, or Staphylococcus aureus. In infant mice with E coli-induced lethal diarrhea and in mice with S aureus and E coli-induced mastitis, ceftiofur was comparable or more active than was ampicillin. [1][2][3]


  • Yancey RJ Jr et al. Am J Vet Res. 1987 Jul; 48(7):1050-3.