Isoconazole nitrate

• Catalog No.: S2534
• CAS Number: 24168-96-5
• M. F.: C18H15Cl4N3O4
• M. W.: 479.1414
• Storage: -20°C

SYNONYMS

• IUPAC name: 1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole; nitric acid
• IUPAC Traditional name: isoconazole; nitric acid
• Synonyms: Adestan G 100; Fazol; Gyno-Travogen

DATABASE IDS

• CAS Number: 24168-96-5

PROPERTIES

• Salt Data: nitrate
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Isoconazole nitrate (Travogen) is an azole antifungal reagent. In a clinic study, a total of 40 coal miners, 35 with culturally proven mycotic infections of the feet and 5 with similarly proven infections of toenails due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes, were treated with 1% cream of either isoconazole nitrate (R 15454; Travogen; Travogyn) for 4 weeks. The clinical cure rates for the isoconazole-treated group for itching, inflammation, scaling and maceration in the cases of foot infections were 89, 88, 83 and 83% respectively. [1][2]

REFERENCES

• Oyeka CA et al. Mycoses. 1992 Nov-Dec; 35(11-12)