L-Ascorbyl 6-palmitate

• Catalog No.: S2532
• CAS Number: 137-66-6
• M. F.: C22H38O7
• M. W.: 414.53292
• Storage: -20°C

SYNONYMS

• IUPAC name: (2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl]-2-hydroxyethyl hexadecanoate
• IUPAC Traditional name: ascorbyl palmitate
• Synonyms: Ascorbic palmitate; Ascorbyl monopalmitate

DATABASE IDS

• CAS Number: 137-66-6

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Cancer
Biological Activity:
L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative. L-Ascorbyl 6-palmitate is an effective preservative in foods and an effective dietary antitumor promoter in mice. Studies indicate that dietary AP is a source of tissue vitamin C in animals. Besides, dietary L-Ascorbyl 6-palmitate possesses weak antiscorbutic activity in guinea pigs and enhances vitamin C nutriture in humans. In a study, daily mean weight loss during repletion in control animals receiving placebo was significantly greater than that for both L-ascorbic acid (AA) and L-Ascorbyl 6-palmitate animals for days 3–10 of repletion. Daily mean weight loss for AP animals was significantly greater than that for AA animals on days 5 and 6 of repletion. By comparing areas of the weight-time curve during repletion, L-Ascorbyl 6-palmitate appeared to be about 50% as effective as AA in reversing scurvy. [1]

REFERENCES

• Jonker D et al. Toxicology. 1988 Nov 30; 52(3)