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Racecadotril

Catalog No. S2503 Name Selleck Chemicals
CAS Number 81110-73-8 Website http://www.selleckchem.com
M. F. C21H23NO4S Telephone (877) 796-6397
M. W. 385.47662 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 73050

SYNONYMS

IUPAC name
benzyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
IUPAC Traditional name
benzyl 2-{2-[(acetylsulfanyl)methyl]-3-phenylpropanamido}acetate
Synonyms
Acetorphan

DATABASE IDS

CAS Number 81110-73-8

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Metabolic Disease
Biological Activity:
Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.Unlike other medications used to treat diarrhea, which reduce intestinal motility, racecadotril has an antisecretory effect—it reduces the secretion of water and electrolytes into the intestine. A small randomized controlled trial found racecadotril to significantly reduce the duration and volume of watery diarrhea in children when given as an adjunct to oral rehydration therapy. [1][2]References on Racecadotril (Acetorphan)[1] Int J Antimicrob Agents., 2000 Feb, 14(1):75-9.[2] http://en.wikipedia.org/wiki/Racecadotril, ,

REFERENCES

  • Schwartz JC et al. Int J Antimicrob Agents. 2000