Pancuronium bromide

• Catalog No.: S2497
• CAS Number: 15500-66-0
• M. F.: C35H60Br2N2O4
• M. W.: 732.6699
• Storage: -20°C

SYNONYMS

• IUPAC name: 1-[(1S,2S,4S,5S,7S,10R,11S,13S,14R,15S)-5,14-bis(acetyloxy)-2,15-dimethyl-13-(1-methylpiperidin-1-ium-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-4-yl]-1-methylpiperidin-1-ium dibromide
• IUPAC Traditional name: pancuronium dibromide
• Synonyms: Pavulon

DATABASE IDS

• CAS Number: 15500-66-0

PROPERTIES

• Salt Data: bromide
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Neurological Disease
Biological Activity:
Pancuronium (Pavulon) is a competitive acetylcholine antagonist with an IC50 of 5.5 ± 0.5 nM.It is a typical non-depolarizing curare-mimetic muscle relaxant. It acts as a competitive acetylcholine antagonist on neuromuscular junctions, displacing acetylcholine (hence competitive) from its post-synaptic nicotinic acetylcholine receptors. It is (unlike suxamethonium) a non-depolarizing agent, which means that it causes no spontaneous depolarizations upon association with the nicotinic receptor in neuromuscular junction, thus producing no muscle fasciculations upon administration. [1][2]

REFERENCES

• http://en.wikipedia.org/wiki/Pancuronium_bromide