Domperidone

• Catalog No.: S2461
• CAS Number: 57808-66-9
• M. F.: C22H24ClN5O2
• M. W.: 425.91126
• Storage: -20°C

SYNONYMS

• IUPAC name: 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
• IUPAC Traditional name: motilium
• Synonyms: Costi; Motillium; Motilium; Motinorm

DATABASE IDS

• CAS Number: 57808-66-9

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Metabolic Disease
Biological Activity:
Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa). [1]References on Domperidone (Motilium)[1] http://en.wikipedia.org/wiki/Domperidone, ,

REFERENCES

• http://en.wikipedia.org/wiki/Domperidone