4-Fluorophenylglyoxal hydrate

• Catalog No.: L20272
• CAS Number: 403-32-7
• M. F.: C8H7FO3
• M. W.: 170.1377832
• Purity: 98%, dry wt. basis

SYNONYMS

• Title: 4-氟苯甲酰甲醛水合物
• IUPAC name: 2-(4-fluorophenyl)-2-oxoacetaldehyde hydrate
• IUPAC Traditional name: 2-(4-fluorophenyl)-2-oxoacetaldehyde hydrate

DATABASE IDS

• Beilstein Number: 2354778
• MDL Number: MFCD01320770
• CAS Number: 403-32-7

PROPERTIES

• Purity: 98%, dry wt. basis
• Melting Point: 84-88°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• RTECS: CY1440000
• Safety Statements: 26-37
• TSCA Listed: 否

REFERENCES

• Aryl glyoxals have been used in the formation of 1,5-disubstituted hydantoins and thiohydantoins; J. Heterocycl. Chem., 18, 1651 (1981); the reaction was subsequently reported to be accelerated under solvent-free conditions using microwaves: Synthesis, 75 (2002).
• Also find extensive use in multi-component reactions to obtain a wide variety of heterocycles including butenolides: Org. Lett., 3, 2875 (2001); oxazoles via a Passerini reaction: Liebigs Ann. Chem., 1107 (1991), and pyrazines via a four-component Ugi reaction: Synthesis, 1553 (2003).