Home > Compound List > Product Information
Benserazide hydrochloride_Molecular_structure_CAS_14919-77-8)
Click picture or here to close

Benserazide hydrochloride

Catalog No. S2453 Name Selleck Chemicals
CAS Number 14919-77-8 Website http://www.selleckchem.com
M. F. C10H16ClN3O5 Telephone (877) 796-6397
M. W. 293.70414 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 73027

SYNONYMS

IUPAC name
2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide hydrochloride
IUPAC Traditional name
benserazide hydrochloride
Synonyms
Ro 4-4602
Serazide

DATABASE IDS

CAS Number 14919-77-8

PROPERTIES

Salt Data hydrochloride
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Benserazide is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor. It inhibits this decarboxylation, and since it itself cannot cross the blood-brain barrier, this allows dopamine to build up solely in the brain instead. Adverse effects caused by peripheral dopamine, such as nausea and arrhythmia, are minimized. However, benserazide cannot reduce the centrally-mediated side effects of levodopa, particularly dyskinesia. [1][2]

REFERENCES

  • http://en.wikipedia.org/wiki/Benserazide