Salidroside(Rhodioloside)

• Catalog No.: S2396
• CAS Number: 10338-51-9
• M. F.: C14H20O7
• M. W.: 300.3044
• Storage: -20°C

SYNONYMS

• IUPAC name: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol
• IUPAC Traditional name: salidroside
• Synonyms: Rhodioloside

DATABASE IDS

• CAS Number: 10338-51-9

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Cancer
Biological Activity:
Salidroside (Rhodioloside; Rhodosin) is a glucoside compound with an IC50 of 4.99 ± 0.23 μg/mL for the proliferation of SACC-2. Salidroside (Rhodioloside; Rhodosin) could inhibit the proliferation of SACC-2 cells and induce SACC-2 cell apoptosis in vitro, which could be a kind of antitumor medicine in the future. Growing curve showed that SACC-2 cells of salidroside groups decreased with extending cell culture time. Immunohistochemistry staining showed that Caspase 3 and Caspase 8 were both strong positive expression in SACC-2 cells of salidroside groups, and poor positive expression in SACC-2 cells of control group, the difference was significant (P<0.01).Salidroside (Rhodioloside; Rhodosin) induces cell-cycle arrest and apoptosis in human breast cancer cells and may be a promising candidate for breast cancer treatment. [1][2][3]

REFERENCES

• Hu X et al. Biochem Biophys Res Commun. 2010 Jul 16;398(1):62-7.