Bromotri(1-pyrrolidinyl)phosphonium hexafluorophosphate

• Catalog No.: L19384
• CAS Number: 132705-51-2
• M. F.: C12H24BrF6N3P2
• M. W.: 466.1810012
• Purity: 97%

SYNONYMS

• Title: 溴-三吡咯烷基磷代六氟磷酸酯
• IUPAC name: bromotris(pyrrolidin-1-yl)phosphanium; hexafluoro-λ^5-phosphanuide
• IUPAC Traditional name: bromotris(pyrrolidin-1-yl)phosphanium hexafluorophosphate
• Synonyms: PyBroP

DATABASE IDS

• Beilstein Number: 7845702
• EC Number: 000-000-0
• MDL Number: MFCD00077412
• CAS Number: 132705-51-2

PROPERTIES

• Purity: 97%
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否

REFERENCES

• Efficient peptide coupling agent for N-methylated amino esters for which coupling with a number of conventional reagents has proved ineffective or slow, and giving superior results to 1H-Benzotriazol-1-yloxytri(1-pyrrolidinyl)phosphonium hexafluorophosphate, B25251, in this type of reaction: J. Org. Chem., 59, 2437 (1994). See Appendix 6.
• Can also be used to activate formamides, e.g. reaction of DMF with primary amines to yield formamidines: Tetrahedron Lett., 40, 5487 (1999).