(R)-(+)-1-Phenylethylamine

• Catalog No.: L19117
• CAS Number: 3886-69-9
• M. F.: C8H11N
• M. W.: 121.17964
• Purity: ChiPros 99+%, ee 99+%

SYNONYMS

• Title: (R)-(+)-1-苯基乙胺
• IUPAC name: (1R)-1-phenylethan-1-amine
• IUPAC Traditional name: D-α-methylbenzylamine
• Synonyms: D-(+)-alpha-Methylbenzylamine

DATABASE IDS

• EC Number: 223-423-4
• MDL Number: MFCD00064405
• Beilstein Number: 2410916
• Merck Index: 146026
• CAS Number: 3886-69-9

PROPERTIES

• Purity: ChiPros 99+%, ee 99+%
• Boiling Point: 187°C
• Density: 0.948
• Flash Point: 71°C(159°F)
• Melting Point: -10°C
• Optical Rotation: +30 (c=10 in ethanol)
• Refractive Index: 1.5260
• GHS Hazard statements: H301-H311-H314-H318-H227
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P210-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
• Risk Statements: 21/22-34
• Safety Statements: 26-36/37/39-45-60
• Storage Warning: Air Sensitive
• TSCA Listed: 是
• Hazard Class: 8
• UN Number: UN2735
• Packing Group: II

REFERENCES

• For use in the enantioselective synthesis of ɑ-amino nitriles and amino acids in the Strecker reaction, see: Chem. Ber., 110, 2098 (1977); J. Org. Chem., 48, 5369 (1983). Similarly, the preformed imines can be reacted with Trimethylsilyl cyanide, A19598: Chem. Lett., 331, 737 (1975). Enantioselective synthesis of cyclohexylamines from 2-alkylcyclohexanones via the imine and reduction: Tetrahedron Lett., 22, 2633 (1981); Chem. Ber., 117, 2076 (1984). Enantioselective synthesis of ɑ-aminoacetals from 1,1-dialkoxy-2-propanones: Synthesis, 608 (1989).
• Both enantiomers are widely used resolving agent for chiral acids. They also find extensive use as chiral auxiliaries in asymmetric synthesis: