Podophyllotoxin

• Catalog No.: S2345
• CAS Number: 518-28-5
• M. F.: C22H22O8
• M. W.: 414.40528
• Storage: -20°C

SYNONYMS

• IUPAC name: (11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one
• IUPAC Traditional name: (11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one
• Synonyms: Podofilox; Condylox

DATABASE IDS

• CAS Number: 518-28-5

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Cancer
Biological Activity:
Podophyllotoxin(Podofilox) is a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. [1]

REFERENCES

• http://www.drugbank.ca/drugs/DB01179