3,4,5-Trifluorobenzeneboronic acid

• Catalog No.: L18519
• CAS Number: 143418-49-9
• M. F.: C6H4BF3O2
• M. W.: 175.9009696
• Purity: 97%

SYNONYMS

• Title: 3,4,5-三氟苯硼酸
• IUPAC name: (3,4,5-trifluorophenyl)boronic acid
• IUPAC Traditional name: 3,4,5-trifluorophenylboronic acid
• Synonyms: 3,4,5-Trifluorophenylboronic acid

DATABASE IDS

• MDL Number: MFCD02093069
• EC Number: 000-000-0
• Beilstein Number: 7371914
• CAS Number: 143418-49-9

PROPERTIES

• Purity: 97%
• Melting Point: 275-279°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• TSCA Listed: 否

REFERENCES

• Extremely active catalyst for the reaction of carboxylic acids with primary and secondary amines to give the corresponding amides in very high yields: J. Org. Chem., 61, 4196 (1996). Also useful in the one-pot synthesis of acyl azides from carboxylic acids and NaN₃: Tetrahedron Lett.,43, 9715 (2002). Mediates the mild, one-pot reduction of carboxylic acids to alcohols with NaBH₄: Tetrahedron Lett., 44, 3427 (2003).
• For other boronic acid chemistry, see Appendix 5.