1-Fluoro-4-hydroxy-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)

• Catalog No.: L17628
• CAS Number: 162241-33-0
• M. F.: C6H13B2F9N2O
• M. W.: 321.7878488
• Purity: ca 45-50% w/w on alumina

SYNONYMS

• Title: 1-氟-4-羟基-1,4-重氮化二环2.2.2辛烷双(四氟硼酸盐)
• IUPAC name: 1-fluoro-4-hydroxy-1,4-diazabicyclo[2.2.2]octane-1,4-diium; bis(tetrafluoroboranuide)
• IUPAC Traditional name: 1-fluoro-4-hydroxy-1,4-diazabicyclo[2.2.2]octane-1,4-diium ditetrafluoroborate
• Synonyms: Accufluor NFTh

DATABASE IDS

• CAS Number: 162241-33-0
• Beilstein Number: 8369351
• MDL Number: MFCD00467883
• EC Number: 418-330-2

PROPERTIES

• Purity: ca 45-50% w/w on alumina
• GHS Hazard statements: H318-H373-H302-H317-H411-H401
• European Hazard Symbols: X
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P260-P261-P305+P351+P338-P302+P352-P321-P501A
• Risk Statements: 22-41-43-48/22-51/53
• Safety Statements: 22-26-36/37/39-61
• TSCA Listed: 否
• Hazard Class: 9
• UN Number: UN3077
• Packing Group: III

REFERENCES

• AccuFluor is a registered trademark of AlliedSignal Inc.
• Versatile, reactive electrophilic fluorinating agent which can be used in water or organic solvents. A variety of substrates such as ketones: Tetrahedron Lett., 37, 3591 (1996), aromatics and enol ethers or enol esters, including steroidal derivatives, can be fluorinated successfully under mild conditions: Tetrahedron Lett., 40, 2673 (1999):
  
• Active methylene compounds (?-diketonesand?-keto esters) are fluorinated in good yield in the presence of zinc chloride and imidazole or collidine. In the presence of water or alcohols, alkenes undergo hydroxy- or alkoxyfluorination to give fluorohydrin derivatives: Tetrahedron Lett., 36, 6769 (1995); 40, 2673 (1999).