Diosmin

• Catalog No.: S2292
• CAS Number: 520-27-4
• M. F.: C28H32O15
• M. W.: 608.54468
• Storage: -20°C

SYNONYMS

• IUPAC name: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one
• IUPAC Traditional name: diosmin

DATABASE IDS

• CAS Number: 520-27-4

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Cardiovascular Disease
Biological Activity:
Diosmin is a semisynthetic phlebotropic agent and a member of the flavonoid family.Diosmin prolongs the vasoconstrictor effect of norepinephrine on the vein wall, increasing venous tone, and therefore reducing venous capacitance, distensibility, and stasis. Diosmin increases the venous return and reduces venous hyperpressure present. Diosmin improves lymphatic drainage by increasing the frequency and intensity of lymphatic contractions, and by increasing the total number of functional lymphatic capillaries. Furthermore, diosmin with hesperidine decreases the diameter of lymphatic capillaries and the intralymphatic pressure. [1]

REFERENCES

• http://en.wikipedia.org/wiki/Diosmin