Berberine Hydrochloride

• Catalog No.: S2271
• CAS Number: 633-65-8
• M. F.: C20H18ClNO4
• M. W.: 371.81422
• Storage: -20°C

SYNONYMS

• IUPAC name: 16,17-dimethoxy-5,7-dioxa-13$l^{5}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-13-ylium chloride
• IUPAC Traditional name: 16,17-dimethoxy-5,7-dioxa-13$l^{5}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-13-ylium chloride

DATABASE IDS

• CAS Number: 633-65-8

PROPERTIES

• Salt Data: Hydrochloride
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Cancer
Biological Activity:
Berberine is a quaternary ammonium salt from the group of isoquinoline alkaloids. It is found in such plants as Berberis, goldenseal (Hydrastis canadensis), and Coptis chinensis, usually in the roots, rhizomes, stems, and bark. Berberine is strongly yellow colored, which is why in earlier times berberis species were used to dye wool, leather and wood. Wool is still today dyed with berberine in Northern India. Under ultraviolet light, berberine shows a strong yellow fluorescence.[1] It inhibited the expression of IL-1beta and TNF-alpha in periodontal tissues in rats periodontitis model and promoted the regeneration of the periodontal tissues. [2]

REFERENCES

• Yu ZH et al. Hua Xi Kou Qiang Yi Xue Za Zhi. 2008 Feb;26(1):82-6.