Artesunate

• Catalog No.: S2265
• CAS Number: 88495-63-0
• M. F.: C19H28O8
• M. W.: 384.42082
• Storage: -20°C

SYNONYMS

• IUPAC name: 4-oxo-4-{[(1S,4S,5R,8S,9R,10R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-yl]oxy}butanoic acid
• IUPAC Traditional name: 4-oxo-4-{[(1S,4S,5R,8S,9R,10R,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-yl]oxy}butanoic acid

DATABASE IDS

• CAS Number: 88495-63-0

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. Artesunate is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. Artesunate is used primarily as treatment for malaria; but artesunate has also been shown to be >90% efficacious at reducing egg production in Schistosoma haematobium infection. [1][2]

REFERENCES

• Boulanger D et al. Trans R Soc Trop Med Hyg. 2007 Feb;101(2):113-6.