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Artemether

Catalog No. S2264 Name Selleck Chemicals
CAS Number 71963-77-4 Website http://www.selleckchem.com
M. F. C16H26O5 Telephone (877) 796-6397
M. W. 298.37464 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72920

SYNONYMS

IUPAC name
(1S,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
IUPAC Traditional name
(1S,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane

DATABASE IDS

CAS Number 71963-77-4

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria. Artemether has been shown to have significant anticancer and antitumor activities. It is demonstrated that artemether caused strong inhibitory effects on brain glioma growth and angiogenesis in rats. Artemether exhibits a dose- and time-dependent cytotoxicity, and induced apoptosis and G2 cell cycle arrest in ovarian cancer cell lines, human leukemia HL60 cells, and human pancreatic cancer BxPC-3 and AsPC-1 cells. [1][2]

REFERENCES

  • Jiao Y et al. Acta Pharmacol Sin. 2007 Jul;28(7):1045-56.