Eaton's Reagent

• Catalog No.: L15607
• CAS Number: 39394-84-8
• M. F.: CH4O8P2S
• M. W.: 238.050182
• Purity: P2O5 ca 7.5% w/w

SYNONYMS

• Title: 伊顿试剂
• IUPAC name: diphosphooxidane; methanesulfonic acid
• IUPAC Traditional name: diphosphooxidane; methanesulfonic acid
• Synonyms: Phosphorus pentoxide, 7.5 wt % in methanesulfonic acid

DATABASE IDS

• CAS Number: 39394-84-8
• MDL Number: MFCD00070545

PROPERTIES

• Purity: P2O5 ca 7.5% w/w
• Density: 1.515
• Flash Point: >110°C(230°F)
• Refractive Index: 1.4350
• GHS Hazard statements: H314-H318-H302
• European Hazard Symbols: X
• European Hazard Symbols: Corrosive (C)
• GHS Precautionary statements: P280-P305+P351+P338-P309-P310
• Risk Statements: 22-34
• Safety Statements: 26-36/37/39-45
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 8
• UN Number: UN3265
• Packing Group: II

REFERENCES

• Lower viscosity alternative to polyphosphoric acid for dehydration and cyclization reactions. Gives high yields in the Beckmann rearrangement: J. Org. Chem., 35, 4071 (1973). For an example of cyclodehydration, see: J. Chem. Soc., Perkin 1, 2956 (1981).
• For further examples and discussion of the utility of this reagent, see: Encyclopedia of Reagents for Organic Synthesis, L. A. Paquette, Ed., Wiley, Chichester (1995), vol. 6, p. 4129.