Magnesium bromide diethyl etherate

• Catalog No.: L15481
• CAS Number: 29858-07-9
• M. F.: C4H10Br2MgO
• M. W.: 258.2346
• Purity: 98%

SYNONYMS

• Title: 乙醚溴化镁
• IUPAC name: magnesium(2+) ion ethoxyethane dibromide
• IUPAC Traditional name: magnesium(2+) ion diethyl ether dibromide

DATABASE IDS

• CAS Number: 29858-07-9
• MDL Number: MFCD00064500

PROPERTIES

• Purity: 98%
• Flash Point: 35°C(95°F)
• GHS Hazard statements: H228
• European Hazard Symbols: Flammable (F)
• GHS Precautionary statements: P210-P241-P280-P240-P370+P378A
• Risk Statements: 11
• Safety Statements: 7-16-33
• Storage Warning: Moisture Sensitive
• TSCA Listed: 否
• Hazard Class: 4.1
• UN Number: UN1325
• Packing Group: II

REFERENCES

• Lewis acid which can influence the regio- and stereochemical outcome of reactions because of its chelating character. Mediates the rearrangement of epoxides to aldehydes and ketones: J. Am. Chem. Soc., 77, 5083 (1955); Tetrahedron Lett., 33, 4457 (1992); or ring-opening to bromohydrins: J. Org. Chem., 61, 3557 (1996); 68, 3660 (2003); Tetrahedron Lett., 45, 5969 (2004). Promotes anti-selectivity in aldol reactions: J. Org. Chem., 56, 5978 (1991). Activates amides to selective N-acylation: Tetrahedron Lett., 43, 647 (2002).
• In combination with Me₂S, promotes chemoselective deprotection of p-methoxybenzyl ethers, in the presence of benzyl or TBDMS ethers, benzoate esters or acetonides: Tetrahedron Lett., 38, 1443 (1997). In the presence of triethylamine, promotes the room-temperature Cannizzaro reaction of aryl and heteroaryl aldehydes to the corresponding alcohol and carboxylic acid: Org. Lett., 7, 5893 (2005).
• For a brief feature on uses of this reagent, see: Synlett, 912 (2004).