Urea hydrogen peroxide adduct

• Catalog No.: L13940
• CAS Number: 124-43-6
• M. F.: CH6N2O3
• M. W.: 94.06994
• Purity: 97%

SYNONYMS

• Title: 脲过氧化氢加合物
• IUPAC name: peroxol; urea
• IUPAC Traditional name: hydrogen peroxide; urea
• Synonyms: Percarbamide; Hydrogen peroxide urea adduct

DATABASE IDS

• MDL Number: MFCD00013119
• EC Number: 204-701-4
• Merck Index: 141782
• Beilstein Number: 3680414
• CAS Number: 124-43-6

PROPERTIES

• Purity: 97%
• Melting Point: ca 90°C dec.
• GHS Hazard statements: H272-H314-H318
• European Hazard Symbols: Corrosive (C)
• European Hazard Symbols: Oxidising (O)
• GHS Precautionary statements: P221-P210-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 8-34
• RTECS: T4860000
• Safety Statements: 17-20-26-36/37/39-45-60
• Storage Warning: Hygroscopic
• TSCA Listed: 是
• Hazard Class: 5.1
• UN Number: UN1511
• Packing Group: III

REFERENCES

• For use in partial oxidation of nitriles to amides, see: Synth. Commun., 23, 3149 (1993).
• In combination with phthalic anhydride is an effective mild and safe oxidant for N-heteroaromatic compounds and tertiary amines to N-oxides: Chem. Ber., 125, 1965 (1992)
• Useful, low-hazard alternative to high-concentration H₂O₂ in epoxidations, Baeyer-Villiger reactions, N-oxidations, etc.: Synlett, 533 (1990). Alkenes can be epoxidized in high yield in 1,1,1,3,3,3-Hexafluoro-2-propanol, A12747 as solvent: Eur. J. Org. Chem., 3290 (2002). For use in combination with N,N'-Dicyclohexylcarbodiimide, A10973, in epoxidation of alkenes, see: J. Org. Chem., 63, 1730 (1998); in combination with Maleic anhydride, A12178, for epoxidation and Baeyer-Villiger reactions: Heterocycles, 36, 1075 (1993). For an extensive review of the Baeyer-Villiger reaction, see: Org. React., 43, 251 (1993).
• Can be used to generate the powerful oxidant peroxytrifluoroacetic acid from TFAA, avoiding the use of hazardous 90% H₂O₂: Tetrahedron Lett., 33, 4835 (1992). The same system has also been reported for oxidation of electron-deficient pyridines to the N-oxides: Tetrahedron Lett., 41, 2299 (2000). Similarly, performic acid can be generated in situ, providing a mild system for oxidation of aromatic aldehydes to benzoic acids: Synth. Commun., 31, 2195 (2001). See also Sodium percarbonate, A16045.