L-tert-Leucine

• Catalog No.: L13707
• CAS Number: 20859-02-3
• M. F.: C6H13NO2
• M. W.: 131.17292
• Purity: 99%

SYNONYMS

• Title: L-叔亮氨酸
• IUPAC name: (2S)-2-amino-3,3-dimethylbutanoic acid
• IUPAC Traditional name: (2S)-2-amino-3,3-dimethylbutanoic acid
• Synonyms: L-2-tert-Butylglycine; (S)-2-Amino-3,3-dimethylbutyric acid

DATABASE IDS

• Beilstein Number: 1721824
• EC Number: 424-750-7
• MDL Number: MFCD00064218
• CAS Number: 20859-02-3

PROPERTIES

• Purity: 99%
• Melting Point: >300°C
• Optical Rotation: +7 (c=5 in 5N HCl)
• TSCA Listed: 否

REFERENCES

• ɑ-Amino acids have been used in combination with NaBH₄ for the asymmetric reduction of ketones. Of a number of amino acids the sterically hindered tert-leucine was found to give the highest ee (95%) in the reduction of the carbonyl group of a 1,5-benzothiazepine intermediate in an efficient synthesis of the calcium antagonist diltiazem: J. Org. Chem., 61, 8586 (1996).