(S)-(+)-3,4,8,8a-Tetrahydro-8a-methyl-1,6(2H,7H)-naphthalenedione

• Catalog No.: L13334
• CAS Number: 33878-99-8
• M. F.: C11H14O2
• M. W.: 178.22766
• Purity: 99%

SYNONYMS

• Title: (S)-(+)-3,4,8,8a-四氢-8a-甲基-1,6-(2H,7H)-萘二酮
• IUPAC name: (8aS)-8a-methyl-1,2,3,4,6,7,8,8a-octahydronaphthalene-1,6-dione
• IUPAC Traditional name: (8aS)-8a-methyl-3,4,7,8-tetrahydro-2H-naphthalene-1,6-dione
• Synonyms: (S)-(+)-9-Methyl-Δ(5,10)-octalin-1,6-dione; (S)-Wieland-Miescher ketone

DATABASE IDS

• MDL Number: MFCD00213797
• Beilstein Number: 1569979
• CAS Number: 33878-99-8

PROPERTIES

• Purity: 99%
• Melting Point: 48-52°C
• Optical Rotation: +100 (c=1 in benzene)
• TSCA Listed: 否

REFERENCES

• Key intermediate in enantioselective steroid syntheses; see, e.g.: Angew. Chem. Int. Ed., 10, 496 (1971); Chem. Ber., 106, 3636 (1973); J. Org. Chem., 45, 2204 (1980).
• For an example of use in synthesis of a diterpene, see: J. Chem. Soc., Perkin 1, 2151 (1986), and of taxane intermediates: J. Org. Chem., 57, 3274 (1992).