Chloroform

• Catalog No.: L13200
• CAS Number: 67-66-3
• M. F.: CHCl3
• M. W.: 119.37764
• Purity: 99%, stab. with 0.8-1% ethanol

SYNONYMS

• Title: 氯仿
• IUPAC name: trichloromethane
• IUPAC Traditional name: chloroform
• Synonyms: Trichloromethane

DATABASE IDS

• Merck Index: 142141
• Beilstein Number: 1731042
• CAS Number: 67-66-3
• MDL Number: MFCD00000826
• EC Number: 200-663-8

PROPERTIES

• Purity: 99%, stab. with 0.8-1% ethanol
• Boiling Point: 60.5-61.5°C
• Density: 1.492
• Melting Point: -63°C
• Refractive Index: 1.4440
• GHS Hazard statements: H351-H373-H302-H315
• European Hazard Symbols: X
• GHS Precautionary statements: P260-P280-P302+P352-P321-P405-P501A
• Risk Statements: 22-38-40-48/20/22
• RTECS: FS9100000
• Safety Statements: 36/37
• TSCA Listed: 是
• Hazard Class: 6.1
• UN Number: UN1888
• Packing Group: III

REFERENCES

• For example of use in the generation of dichlorocarbene under phase-transfer catalysis, see: Org. Synth. Coll., 7, 12 (1990). See also Bromoform, A11904.
• In the presence of base, phenols undergo formylation predominantly in the ortho-position, to give salicylaldehyde derivatives (the Reimer-Tiemann reaction). The mechanism probably involves dichlorocarbene, and yields are generally rather low. For an example, see: Org. Synth. Coll., 3, 463 (1955); review: Org. React., 28, (1982). Improved procedures have been reported: Synth. Commun., 18, 2095 (1988); and, using ultrasound: Synth. Commun., 20, 609 (1990); for an example, see 4-Chlorophenol, A15602.