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Chlormezanone

Catalog No. S2021 Name Selleck Chemicals
CAS Number 80-77-3 Website http://www.selleckchem.com
M. F. C11H12ClNO3S Telephone (877) 796-6397
M. W. 273.73588 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 1049

SYNONYMS

IUPAC name
2-(4-chlorophenyl)-3-methyl-1$l^{6},3-thiazinane-1,1,4-trione
IUPAC Traditional name
chlormezanone
Synonyms
Trancopal

DATABASE IDS

CAS Number 80-77-3

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Chlormezanone(Trancopal),a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm. Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitter GABA, increasing the inhibition of the ascending reticular activating system and blocking the cortical and limbic arousal that occurs following stimulation of the reticular pathways. [1]

REFERENCES

  • http://www.drugbank.ca/drugs/DB01178