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Taurine

Catalog No. S2008 Name Selleck Chemicals
CAS Number 107-35-7 Website http://www.selleckchem.com
M. F. C2H7NO3S Telephone (877) 796-6397
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Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 1723

SYNONYMS

IUPAC name
2-aminoethane-1-sulfonic acid
IUPAC Traditional name
2-aminoethanesulfonic acid
Synonyms
2-Aminoethanesulfonic acid

DATABASE IDS

CAS Number 107-35-7

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area
Description Cardiovascular Disease
Biological Activity
Description Taurine is an organic acid widely distributed in animal tissues.
Targets
IC50
In Vitro Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms. [1] In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. [2] In addition, Taurine is an essential nutrient for the cat. [3] Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function. [4]
In Vivo
Clinical Trials
Features
References
[1] Huxtable RJ. Prog Neurobiol, 1989, 32(6), 471-533.
[2] Chesney RW. Adv Pediatr, 1985, 32, 1-42.
[3] Knopf K, et al. J Nutr, 1978, 108(5), 773-778.
[4] Pion PD, et al. Science, 1987, 237(4816), 764-768.