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Sodium butyrate

Catalog No. S1999 Name Selleck Chemicals
CAS Number 156-54-7 Website http://www.selleckchem.com
M. F. C4H7NaO2 Telephone (877) 796-6397
M. W. 110.08695 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72833

SYNONYMS

IUPAC name
sodium butanoate
IUPAC Traditional name
butanoic acid, sodium salt
Synonyms
Butyric acid sodium salt

DATABASE IDS

CAS Number 156-54-7

PROPERTIES

Salt Data Butyrate
Solubility DMSO
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Cancer
Biological Activity:
Sodium butyrate is a compound with formula Na(C3H7COO). It is the sodium salt of butyric acid. It has various effects on cultured mammalian cells including inhibition of proliferation, induction of differentiation and induction or repression of gene expression. As such, it can be used in lab to bring about any of these effects. Specifically, butyrate treatment of cells results in histone hyperacetylation, and butyrate itself inhibits HDAC activity. Butyrate has been an essential vehicle for determining the role of histone acetylation in chromatin structure and function. Inhibition of HDAC activity affects the expression of only 2% of mammalian genes. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Sodium_butyrate