5-Nitrothiophene-2-carbonitrile

• Catalog No.: L11058
• CAS Number: 16689-02-4
• M. F.: C5H2N2O2S
• M. W.: 154.14658
• Purity: 98+%

SYNONYMS

• Title: 5-硝基噻酚-2-甲腈
• IUPAC name: 5-nitrothiophene-2-carbonitrile
• IUPAC Traditional name: 5-nitrothiophene-2-carbonitrile
• Synonyms: 2-Cyano-5-nitrothiophene

DATABASE IDS

• Beilstein Number: 123934
• CAS Number: 16689-02-4
• EC Number: 000-000-0
• MDL Number: MFCD00052401

PROPERTIES

• Purity: 98+%
• Melting Point: 43-45°C
• GHS Hazard statements: H331-H302-H312-H315-H319-H335
• European Hazard Symbols: X
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 20/21/22-36/37/38
• Safety Statements: 9-26-36/37
• TSCA Listed: 否
• Hazard Class: 6.1
• UN Number: UN3439
• Packing Group: III

REFERENCES

• For a review of vicarious nucleophilic substitution in heterocyclic compounds, see: Synthesis, 103 (1991).
• Undergoes vicarious nucleophilic substitution at the 4-position; e.g. with chloromethyl phenyl sulfone and base, 5-nitro-4-(phenylsulfonylmethyl)thiophene-2-carbonitrile is formed in 91% yield: Tetrahedron, 51, 8339 (1995). For analogous example and reaction scheme, see 2-Nitrothiophene, A17464.