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Triamcinolone

Catalog No. S1933 Name Selleck Chemicals
CAS Number 124-94-7 Website http://www.selleckchem.com
M. F. C21H27FO6 Telephone (877) 796-6397
M. W. 394.4338832 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 502

SYNONYMS

IUPAC name
(1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
IUPAC Traditional name
triamcinolone
Synonyms
Kenacort
Azmacort
Triaderm
Tri-Nasal

DATABASE IDS

CAS Number 124-94-7

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Inflammation
Biological Activity:
Triamcinolone(Aristocort) is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition of arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. [1]

REFERENCES

  • http://www.drugbank.ca/drugs/DB00620