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Sulfamethoxazole

Catalog No. S1915 Name Selleck Chemicals
CAS Number 723-46-6 Website http://www.selleckchem.com
M. F. C10H11N3O3S Telephone (877) 796-6397
M. W. 253.27764 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 888

SYNONYMS

IUPAC name
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide
IUPAC Traditional name
sulfamethoxazole
Synonyms
Gantanol
Gantanol DS

DATABASE IDS

CAS Number 723-46-6

PROPERTIES

Target DNA/RNA
Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 μM. Sulfamethoxazole is most often used as a part of synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole. Sulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. [1][2]

REFERENCES

  • http://en.wikipedia.org/wiki/Sulfamethoxazole