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Tropisetron hydrochloride_Molecular_structure_CAS_105826-92-4)
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Tropisetron hydrochloride

Catalog No. S1898 Name Selleck Chemicals
CAS Number 105826-92-4 Website http://www.selleckchem.com
M. F. C17H21ClN2O2 Telephone (877) 796-6397
M. W. 320.81384 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72818

SYNONYMS

IUPAC name
(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3H-indole-3-carboxylate hydrochloride
IUPAC Traditional name
(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3H-indole-3-carboxylate hydrochloride
Synonyms
ICS 205930
Navoban

DATABASE IDS

CAS Number 105826-92-4

PROPERTIES

Salt Data HCL
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Neurological Disease
Biological Activity:
Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor. [1] It is used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. [2]

REFERENCES

  • Rothlin CV et al. Mol Pharmacol. 2003 May; 63(5)