Bromomethyl methyl ether

• Catalog No.: L09837
• CAS Number: 13057-17-5
• M. F.: C2H5BrO
• M. W.: 124.9645
• Purity: tech. 90%

SYNONYMS

• Title: 溴甲基甲醚
• IUPAC name: bromo(methoxy)methane
• IUPAC Traditional name: methane, bromomethoxy-
• Synonyms: BMME; Methoxymethyl bromide

DATABASE IDS

• CAS Number: 13057-17-5
• MDL Number: MFCD00000171
• Beilstein Number: 1730853

PROPERTIES

• Purity: tech. 90%
• Boiling Point: 86-87°C
• Density: 1.531
• Flash Point: 26°C(78°F)
• Refractive Index: 1.4520-1.4600
• GHS Hazard statements: H331-H302-H312-H315-H319-H335-H226-H351
• European Hazard Symbols: X
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-20/21/22-36/37/38-40
• Safety Statements: 16-26-36/37
• TSCA Listed: 是
• Hazard Class: 3
• UN Number: UN1992
• Packing Group: II

REFERENCES

• Reagent for protection of OH groups as their methoxymethyl (MOM) ethers. The group can be introduced in the presence of a base such as N-ethyldiisopropylamine: Tetrahedron Lett., 26, 6461 (1986); 30, 1971 (1989). Aryl acetates are converted directly into aryl methoxymethyl ethers in the presence of NaOMe in DMF: Synth. Commun., 29, 2217 (1999).
• A method for the ɑ-methylenation of lactones involves alkylation of the ɑ-lithio derivative, followed by elimination of methanol: J. Am. Chem. Soc., 102, 3964 (1980).
• For a review of the use of ɑ-monohalo ethers in synthesis, see: Synthesis, 1 (1995).