Triisopropylsilane

• Catalog No.: L09585
• CAS Number: 6485-79-6
• M. F.: C9H22Si
• M. W.: 158.35648
• Purity: 98%

SYNONYMS

• Title: 三异丙基硅烷
• IUPAC name: tris(propan-2-yl)silane
• IUPAC Traditional name: triisopropylsilane
• Synonyms: TIS

DATABASE IDS

• CAS Number: 6485-79-6
• Beilstein Number: 1733718
• MDL Number: MFCD00009657

PROPERTIES

• Purity: 98%
• Boiling Point: 166°C
• Density: 0.773
• Flash Point: 35°C(95°F)
• Refractive Index: 1.4340
• GHS Hazard statements: H226-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• Risk Statements: 10-36/37/38
• Safety Statements: 23-26-37-60
• TSCA Listed: 否
• Hazard Class: 3
• UN Number: UN1993
• Packing Group: III

REFERENCES

• Selective silylation of primary OH groups in the presence of secondary has been carried out with this reagent in combination with CsF and imidazole: J. Organomet. Chem., 282, 155 (1985). See Appendix 4.
• Triethylsilane and triisopropylsilane have been studied as cation scavengers in the deprotection of peptides with TFA, and were found to give good results, with triisopropylsilane being particularly effective in trapping trityl cations in the TFA deprotection of cysteine containing peptides. The use of triisopropylsilane minimizes the risk of reduction of the indole nucleus in tryptophan-containing peptides: Tetrahedron Lett., 30, 2739 (1989). See Appendix 6.