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Ranitidine Hydrochloride

Catalog No. S1801 Name Selleck Chemicals
CAS Number 66357-59-3 Website http://www.selleckchem.com
M. F. C13H23ClN4O3S Telephone (877) 796-6397
M. W. 350.86472 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72805

SYNONYMS

IUPAC name
[(E)-1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}amino)-2-nitroethenyl](methyl)amine hydrochloride
IUPAC Traditional name
[(E)-1-({2-[({5-[(dimethylamino)methyl]furan-2-yl}methyl)sulfanyl]ethyl}amino)-2-nitroethenyl](methyl)amine hydrochloride
Synonyms
Zantac
Azantac
AH 19065

DATABASE IDS

CAS Number 66357-59-3

PROPERTIES

Salt Data Hydrochloride
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Metabolic Disease
Biological Activity:
Ranitidine (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 µM. It inhibits stomach acid production. It is also used alongside fexofenadine and other antihistamines for the treatment of skin conditions such as hives. It has 10% the affinity that cimetidine has to CYP450 so it causes fewer side effects, but other H2 blockers famotidine and nizatidine have no CYP450 significant interactions. [1][2]

REFERENCES

  • Herling AW et al. Agents Actions. 1987 Feb;20(1-2)