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Vidarabine

Catalog No. S1784 Name Selleck Chemicals
CAS Number 5536-17-4 Website http://www.selleckchem.com
M. F. C10H13N5O4 Telephone (877) 796-6397
M. W. 267.24132 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 79

SYNONYMS

IUPAC name
(2R,3S,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
IUPAC Traditional name
armes
Synonyms
Vira-A

DATABASE IDS

CAS Number 5536-17-4

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Infection
Biological Activity:
Vidarabine(Vira-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses. Vidarabine works by interfering with the synthesis of viral DNA. It is a nucleoside analog, therefore it has to be phosphorylated and to be active. Vidarabine stops replication of herpes viral DNA in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, 3) inactivation of the viral DNA polymerase. [1]

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