3-Benzyl-5-(2-hydroxyethyl)-4-methylthiazolium chloride

• Catalog No.: L08750
• CAS Number: 4568-71-2
• M. F.: C13H16ClNOS
• M. W.: 269.79024
• Purity: 98%

SYNONYMS

• Title: 3-苄基-5-(2-羟基乙基)-4-甲基噻唑鎓氯化物
• IUPAC name: 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
• IUPAC Traditional name: 3-benzyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride

DATABASE IDS

• Beilstein Number: 3788921
• EC Number: 224-947-6
• CAS Number: 4568-71-2
• MDL Number: MFCD00011959

PROPERTIES

• Purity: 98%
• Melting Point: 142-145°C
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• Risk Statements: 36/37/38
• Safety Statements: 26-37
• Storage Warning: Hygroscopic
• TSCA Listed: 否

REFERENCES

• For reviews, see: Angew. Chem. Int. Ed., 15, 639 (1976); Org. React., 40, 407 (1991). For a further example, see Phenyl vinyl sulfone, A14794.
• Aliphatic aldehydes undergo the acyloin condensation in the presence of this catalyst and mild base. For example (butyraldehyde to butyroin), see: Org. Synth. Coll., 7, 95 (1990).
• The same system is effective in catalyzing the addition of aldehydes to electron-deficient alkenes, including ɑ?-unsaturated ketones, esters and nitriles (Stetter reaction), providing a non-toxic alternative to cyanide in these reactions; e.g. in the synthesis of dihydrojasmone: Org. Synth. Coll., 8, 620 (1993):