Rifapentine

• Catalog No.: S1760
• CAS Number: 61379-65-5
• M. F.: C47H64N4O12
• M. W.: 877.03066
• Storage: -20°C

SYNONYMS

• IUPAC name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-26-[(E)-N-(4-cyclopentylpiperazin-1-yl)carboximidoyl]-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl acetate
• IUPAC Traditional name: @rifapentine
• Synonyms: Priftin; Cyclopentylrifampicin

DATABASE IDS

• CAS Number: 61379-65-5

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Rifapentine (Priftin) is an antibiotic compound used in the treatment of tuberculosis. Treatment begins in an intensive phase of twice-weekly dosing, followed by a maintenance phase of once-weekly dosing. Rifapentine (Priftin) is an antibiotic that kills the bacterium that causes tuberculosis, Mycobacterium tuberculosis. Rifapentine (Priftin) targets DNA-dependent RNA polymerase — proteins that are necessary for RNA synthesis and the production of proteins. This process is different in human (eukaryotic) cells and bacteria; rifamycins, like rifapentine, only affects this process in bacteria. [1]

REFERENCES

• http://en.wikipedia.org/wiki/Rifapentine