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Pitavastatin calcium

Catalog No. S1759 Name Selleck Chemicals
CAS Number 147526-32-7 Website http://www.selleckchem.com
M. F. C50H46CaF2N2O8 Telephone (877) 796-6397
M. W. 880.9836464 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 72797

SYNONYMS

IUPAC name
calcium bis((3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate)
IUPAC Traditional name
calcium(2+) bis((3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate)
Synonyms
Livalo

DATABASE IDS

CAS Number 147526-32-7

PROPERTIES

Salt Data Calcium
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Cardiovascular Disease
Biological Activity:
Pitavastatin calcium(Livalo) is a novel member of the medication class of statins. Like the other statins, it is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis. Most statins are metabolised in part by one or more hepatic cytochrome P450 enzymes, leading to an increased potential for drug interactions and problems with certain foods (such as grapefruit juice). Pitavastatin appears to be a substrate of CYP2C9, and not CYP3A4 (which is a common source of interactions in other statins). [1] 

REFERENCES

  • http://en.wikipedia.org/wiki/Pitavastatin