Rifabutin

• Catalog No.: S1741
• CAS Number: 72559-06-9
• M. F.: C46H62N4O11
• M. W.: 847.00468
• Storage: -20°C

SYNONYMS

• IUPAC name: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23,32-trioxo-8,33-dioxa-24,27,29-triazaspiro[pentacyclo[23.6.1.1^{4,7}.0^{5,31}.0^{26,30}]tritriacontane-28,4'-piperidin]-1(31),2,4,9,19,21,25,29-octaen-13-yl acetate
• IUPAC Traditional name: @rifabutin
• Synonyms: Ansatipine; LM 427; Ansamycin; Mycobutin

DATABASE IDS

• CAS Number: 72559-06-9

PROPERTIES

• Salt Data: Free Base
• Storage Condition: -20°C

DETAILS

Description (English)

Research Area: Infection
Biological Activity:
Rifabutin(Mycobutin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. [1, 2]

REFERENCES

• http://en.wikipedia.org/wiki/Rifabutin