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Telmisartan

Catalog No. S1738 Name Selleck Chemicals
CAS Number 144701-48-4 Website http://www.selleckchem.com
M. F. C33H30N4O2 Telephone (877) 796-6397
M. W. 514.6169 Fax (832) 582-8590
Purity Email sales@selleckchem.com
Storage -20°C Chembase ID: 841

SYNONYMS

IUPAC name
2-(4-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
IUPAC Traditional name
telmisartan
Synonyms
Micardis
Temax
Targit
BIBR277

DATABASE IDS

CAS Number 144701-48-4

PROPERTIES

Salt Data Free Base
Storage Condition -20°C

DETAILS

Description (English)
Research Area: Cardiovascular Disease
Biological Activity:
Telmisartan o(Micardis) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. In addition to blocking the Renin-Angiotensin System (RAS), telmisartan acts as a selective modulator of Peroxisome proliferator-activated receptor gamma (PPAR-γ), a central regulator of insulin and glucose metabolism. Telmisartan has binding affinity 3000 times greater for AT1 than AT2 receptors. Telmisartan also has the longest half life (24 hrs) of all angiotensin II type 1 receptor antagonists. [1]

REFERENCES

  • http://en.wikipedia.org/wiki/Telmisartan